The brain thermoregulation is an important issue from anthropology to medicine. The brain thermodynamic mechanisms in humans are still not well known and additional heat regulations in certain physiological and pathological conditions are crucial to prevent irreversible damages. Namely hyperthermia is a life-threatening condition causing severe functional alterations. The brain temperature can increase as a consequence of drug abuse, head injuries, strokes, etc. Releasing of the heat stress can be treated by plenty of invasive and non-invasive methods, systemic or selectively aimed. However, establishing new effective thermodynamic techniques to treat pathological conditions is still relevant issue. In craniotomies, the cooling method can consist of simple system of drainage tubes directly attached to the dural layers or brain passing a cooling liquid directly to the affected tissue. Such selectively aimed device can help the post-operative recovery and prevent possible complications. The principles of the device remotely reminds of radiator theory, possible thermoregulatory adaptation in human lineage ancestors proposed in paleoanthropology few decades ago.